Jump to:
loading...| Preferred Name |
Lincosamide Antibiotic |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82922 |
| code |
C82922 |
| DEFINITION |
Any synthetic or semi-synthetic derivative of lincomycin, first isolated from a soil actinomycete Streptomyces lincolnensis, with antibacterial activity. Lincosamide antibiotics bind to the 23S rRNA in the large 50S subunit of bacterial ribosomes, thereby preventing the peptidyl-tRNA translocation from the A site to the P site. This results in peptidyl-tRNA dissociation from ribosomes, and leads to the release of incomplete proteins, ultimately causing cell death. |
| label |
Lincosamide Antibiotic |
| Legacy_Concept_Name |
Lincosamide_Antibiotic |
| Preferred_Name |
Lincosamide Antibiotic |
| prefixIRI |
C82922 |
| prefLabel |
Lincosamide Antibiotic |
| Semantic_Type |
Chemical Viewed Functionally |
| UMLS_CUI |
C2826567 |
| subClassOf |
Create New Mapping
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||