National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Nucleoside Reverse Transcriptase Inhibitor
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97452
code	C97452
DEFINITION	A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase resulting in inhibition of enzyme function, chain termination, and inhibition of viral replication. These compounds are converted to their active phosphorylated forms by cellular kinases.
FULL_SYN	Nucleoside Analog Reverse Transcriptase Inhibitor NRTI
label	Nucleoside Reverse Transcriptase Inhibitor
Preferred_Name	Nucleoside Reverse Transcriptase Inhibitor
prefixIRI	C97452
prefLabel	Nucleoside Reverse Transcriptase Inhibitor
Semantic_Type	Chemical Viewed Functionally
UMLS_CUI	C1373111
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1589

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Delete	Mapping To	Ontology	Source
	There are currently no mappings for this class.