Non-nucleoside Reverse Transcriptase Inhibitor

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97453

C97453

A substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase. These compounds do not bind to the active site of the polymerase but in a less conserved pocket near the active site, causing a distortion in the shape of the active site and resulting in inhibition of enzymatic function, chain termination, and inhibition of viral replication.

NNRTI

Non-nucleoside Reverse Transcriptase Inhibitor

Non-nucleoside Reverse Transcriptase Inhibitor

C97453

Non-nucleoside Reverse Transcriptase Inhibitor

Chemical Viewed Functionally

C1373120

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1589