Phenotypic Quality Ontology

Last uploaded: March 1, 2022
Preferred Name

professional antigen presenting cell

Synonyms

APC

Definitions

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.

ID

http://purl.obolibrary.org/obo/CL_0000145

comment

Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.

capable of

http://purl.obolibrary.org/obo/GO_0002504

definition

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.

has_broad_synonym

APC

has_obo_namespace

cell

label

professional antigen presenting cell

prefixIRI

CL:0000145

prefLabel

professional antigen presenting cell

subClassOf

http://purl.obolibrary.org/obo/CL_0000738

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http://purl.obolibrary.org/obo/CL_0000145 Cell Ontology LOOM
http://purl.obolibrary.org/obo/CL_0000145 Cell Ontology SAME_URI
http://purl.obolibrary.org/obo/CL_0000145 Human Disease Ontology 123 LOOM
http://purl.obolibrary.org/obo/CL_0000145 Human Disease Ontology 123 SAME_URI