loading...| Preferred Name |
mitogen-activated protein kinase |
| Synonyms |
MAPK kinase-related transforming protein |
| Definitions |
A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY. Category=family. |
| ID |
http://purl.obolibrary.org/obo/PR_000000019 |
| comment |
Category=family. |
| database_cross_reference |
PIRSF:PIRSF501110 |
| definition |
A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY. |
| has_exact_synonym |
MAPK |
| has_obo_namespace |
protein |
| has_related_synonym |
kinase-related transforming protein |
| id |
PR:000000019 |
| label |
mitogen-activated protein kinase |
| notation |
PR:000000019 |
| prefLabel |
mitogen-activated protein kinase |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16376 | National Cancer Institute Thesaurus | LOOM |