loading...| Preferred Name |
integrin alpha-M |
| Synonyms |
neutrophil adherence receptor cell surface glycoprotein MAC-1 subunit alpha ITGAM CR3A CD11b leukocyte adhesion receptor MO1 CD11 antigen-like family member B CR-3 alpha chain |
| Definitions |
Category=gene. Requested by=CL. An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. |
| ID |
http://purl.obolibrary.org/obo/PR_000001012 |
| comment |
Category=gene. Requested by=CL. |
| database_cross_reference |
IUPHARobj:2452 |
| definition |
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. |
| has_exact_synonym |
neutrophil adherence receptor cell surface glycoprotein MAC-1 subunit alpha ITGAM CD11b leukocyte adhesion receptor MO1 CD11 antigen-like family member B CR-3 alpha chain |
| has_obo_namespace |
protein |
| has_related_synonym |
CR3A |
| id |
PR:000001012 |
| label |
integrin alpha-M |
| notation |
PR:000001012 |
| prefLabel |
integrin alpha-M |
| treeView | |
| subClassOf |