loading...| Preferred Name |
tumor necrosis factor superfamily mediated signaling pathway |
| Synonyms |
TNF superfamily mediated signaling pathway |
| Definitions |
Members of TNF superfamily mediate autoimmunity and inflammation, cell proliferation, survival and/or apoptosis through a number of signaling mechanisms that involve activation of nuclear factor-kappaB, of caspases and/or of mitogen-activated protein kinases (MAPK). TNF superfamily has been implicated in a wide range of human diseases including tumorigenesis, septic shock, rheumatoid arthritis and other conditions. |
| ID |
http://purl.obolibrary.org/obo/PW_0000236 |
| definition |
Members of TNF superfamily mediate autoimmunity and inflammation, cell proliferation, survival and/or apoptosis through a number of signaling mechanisms that involve activation of nuclear factor-kappaB, of caspases and/or of mitogen-activated protein kinases (MAPK). TNF superfamily has been implicated in a wide range of human diseases including tumorigenesis, septic shock, rheumatoid arthritis and other conditions. |
| has_obo_namespace |
pathway |
| has_related_synonym |
TNF superfamily mediated signaling pathway |
| id |
PW:0000236 |
| label |
tumor necrosis factor superfamily mediated signaling pathway |
| notation |
PW:0000236 |
| prefLabel |
tumor necrosis factor superfamily mediated signaling pathway |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| There are currently no mappings for this class. | |||