Pathway Ontology

Last uploaded: January 13, 2022
Preferred Name

classical cadherin signaling pathway

Definitions

Classical cadherins, such as E- or N-cadherin are single-span transmembrane proteins with five extracellular cadherin repeats and a conserved cytoplasmic tail. Their interaction with many cytoskeletal and signaling molecules underlies the calcium-dependent cell-cell adhesion and signaling. While E- and N-cadherin share some of the interacting partners, they have different localization and impact on distinct cellular events.

ID

http://purl.obolibrary.org/obo/PW_0000988

created_by

VPetri

creation_date

2012-05-25T10:07:46Z

definition

Classical cadherins, such as E- or N-cadherin are single-span transmembrane proteins with five extracellular cadherin repeats and a conserved cytoplasmic tail. Their interaction with many cytoskeletal and signaling molecules underlies the calcium-dependent cell-cell adhesion and signaling. While E- and N-cadherin share some of the interacting partners, they have different localization and impact on distinct cellular events.

has_obo_namespace

pathway

id

PW:0000988

label

classical cadherin signaling pathway

notation

PW:0000988

prefLabel

classical cadherin signaling pathway

treeView

http://purl.obolibrary.org/obo/PW_0000333

subClassOf

http://purl.obolibrary.org/obo/PW_0000333

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