Sequence Types and Features Ontology

Last uploaded: January 23, 2019
Preferred Name

CRM

Synonyms

transcription factor module

TF module

cis regulatory module

Definitions

A regulatory region where transcription factor binding sites clustered to regulate various aspects of transcription activities. (CRMs can be located a few kb to hundred kb upstream of the basal promoter, in the coding sequence, within introns, or in the downstream 3'UTR sequences, as well as on different chromosome). A single gene can be regulated by multiple CRMs to give precise control of its spatial and temporal expression. CRMs function as nodes in large, intertwined regulatory network. Requested by Stephen Grossmann Dec 2004.

ID

http://purl.obolibrary.org/obo/SO_0000727

comment

Requested by Stephen Grossmann Dec 2004.

definition

A regulatory region where transcription factor binding sites clustered to regulate various aspects of transcription activities. (CRMs can be located a few kb to hundred kb upstream of the basal promoter, in the coding sequence, within introns, or in the downstream 3'UTR sequences, as well as on different chromosome). A single gene can be regulated by multiple CRMs to give precise control of its spatial and temporal expression. CRMs function as nodes in large, intertwined regulatory network.

has_exact_synonym

transcription factor module

TF module

cis regulatory module

has_obo_namespace

sequence

id

SO:0000727

in_subset

http://purl.obolibrary.org/obo/so#SOFA

label

CRM

notation

SO:0000727

prefLabel

CRM

has_part

http://purl.obolibrary.org/obo/SO_0000235

subClassOf

http://purl.obolibrary.org/obo/SO_0001055

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