loading...| Preferred Name |
tuberculosis |
| Synonyms |
active tuberculosis Kochs disease tuberculosis disease TB |
| Definitions |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
| ID |
http://purl.obolibrary.org/obo/MONDO_0018076 |
| database_cross_reference |
UMLS:C0151332 SCTID:56717001 COHD:434557 DOID:399 MedDRA:10044755 ICD9:017.96 ICD9:017.94 ICD10:A15.A19 Orphanet:3389 ICD9:017.90 UMLS:C0041296 GARD:0007827 NCIT:C3423 ICD9:017.92 MESH:D014376 |
| definition |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
| exactMatch |
http://identifiers.org/mesh/D014376 http://purl.obolibrary.org/obo/DOID_399 http://www.orpha.net/ORDO/Orphanet_3389 http://linkedlifedata.com/resource/umls/id/C0041296 http://identifiers.org/meddra/10044755 http://identifiers.org/snomedct/56717001 |
| has_exact_synonym |
active tuberculosis tuberculosis disease |
| has_related_synonym |
Kochs disease TB |
| id |
MONDO:0018076 |
| imported from | |
| in_subset | |
| label |
tuberculosis |
| notation |
MONDO:0018076 |
| prefLabel |
tuberculosis |
| seeAlso |
https://rarediseases.info.nih.gov/diseases/7827/tuberculosis |
| subClassOf |