Cell Ontology

Last uploaded: February 23, 2022
Preferred Name

integrin alpha-X

Synonyms

CD11C

CD11c

leukocyte adhesion receptor p150,95

Leu M5

CD11 antigen-like family member C

ITGAX

leukocyte adhesion glycoprotein p150,95 alpha chain

Definitions

Category=gene. Requested by=CL. An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

ID

http://purl.obolibrary.org/obo/PR_000001013

comment

Category=gene. Requested by=CL.

database_cross_reference

IUPHARobj:2454

definition

An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

has_exact_synonym

CD11c

leukocyte adhesion receptor p150,95

Leu M5

CD11 antigen-like family member C

ITGAX

leukocyte adhesion glycoprotein p150,95 alpha chain

has_obo_namespace

protein

has_related_synonym

CD11C

id

PR:000001013

label

integrin alpha-X

notation

PR:000001013

prefLabel

integrin alpha-X

subClassOf

http://purl.obolibrary.org/obo/PR_000001005

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http://purl.obolibrary.org/obo/PR_000001013 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001013 Phenotypic Quality Ontology SAME_URI
http://purl.obolibrary.org/obo/PR_000001013 Protein Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001013 Protein Ontology SAME_URI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16789 National Cancer Institute Thesaurus LOOM
http://purl.bioontology.org/ontology/OMIM/151510 Online Mendelian Inheritance in Man LOOM