Human Phenotype Ontology

Last uploaded: February 24, 2022
Preferred Name

Acanthosis nigricans

Synonyms

Keratosis nigricans

Darkened and thickened skin

Definitions

Acanthosis nigricans is seen in a variety of syndromes including those characterized by insulin resistance or fibroblast growth factor receptor (FGFR) mutations, and may also occur as an adverse effect of several medications that promote hyperinsulinemia. A dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck.

ID

http://purl.obolibrary.org/obo/HP_0000956

comment

Acanthosis nigricans is seen in a variety of syndromes including those characterized by insulin resistance or fibroblast growth factor receptor (FGFR) mutations, and may also occur as an adverse effect of several medications that promote hyperinsulinemia.

database_cross_reference

SNOMEDCT_US:402599005

UMLS:C0000889

SNOMEDCT_US:72129000

MSH:D000052

definition

A dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck.

has_alternative_id

HP:0007518

HP:0007498

HP:0007591

has_exact_synonym

Keratosis nigricans

Darkened and thickened skin

has_obo_namespace

human_phenotype

id

HP:0000956

in_subset

http://purl.obolibrary.org/obo/hp.obo#secondary_consequence

label

Acanthosis nigricans

notation

HP:0000956

prefLabel

Acanthosis nigricans

treeView

http://purl.obolibrary.org/obo/HP_0011368

subClassOf

http://purl.obolibrary.org/obo/HP_0011368

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