Human Phenotype Ontology

Last uploaded: February 24, 2022
Preferred Name

Schizophrenia

Definitions

Positive symptoms, such as delusions and hallucinations (especially of voices), are common, and any Schneiderian first-rank symptoms are particularly indicative of the illness. Negative symptoms include social withdrawal, impairment of ego boundaries, and loss of energy and initiative. Schizophrenia is diagnosed only if symptoms persist for at least one month. The illness can spontaneously remit, run a course with infrequent or frequent relapses, or become chronic. The prognosis has improved with antipsychotic drugs and with vigorous psychological and social management and rehabilitation. The many causes include genetic factors, environmental stress, and various triggering factors. A mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social or occupational dysfunction. The onset of symptoms typically occurs in young adulthood, with a global lifetime prevalence of about 0.3-0.7%.

ID

http://purl.obolibrary.org/obo/HP_0100753

comment

Positive symptoms, such as delusions and hallucinations (especially of voices), are common, and any Schneiderian first-rank symptoms are particularly indicative of the illness. Negative symptoms include social withdrawal, impairment of ego boundaries, and loss of energy and initiative. Schizophrenia is diagnosed only if symptoms persist for at least one month. The illness can spontaneously remit, run a course with infrequent or frequent relapses, or become chronic. The prognosis has improved with antipsychotic drugs and with vigorous psychological and social management and rehabilitation. The many causes include genetic factors, environmental stress, and various triggering factors.

created_by

doelkens

creation_date

2011-06-07T09:53:08Z

database_cross_reference

MSH:D012559

SNOMEDCT_US:58214004

SNOMEDCT_US:191526005

UMLS:C0036341

definition

A mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social or occupational dysfunction. The onset of symptoms typically occurs in young adulthood, with a global lifetime prevalence of about 0.3-0.7%.

has_obo_namespace

human_phenotype

id

HP:0100753

label

Schizophrenia

notation

HP:0100753

prefLabel

Schizophrenia

treeView

http://purl.obolibrary.org/obo/HP_0000708

subClassOf

http://purl.obolibrary.org/obo/HP_0000708

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http://purl.bioontology.org/ontology/ICD10/F20 International Classification of Diseases, Version 10 LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU015654 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/HP_0100753 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/HP_0100753 International Classification of Diseases Ontology SAME_URI
http://purl.bioontology.org/ontology/MESH/D012559 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/LNC/LA10584-3 Logical Observation Identifier Names and Codes LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3362 National Cancer Institute Thesaurus LOOM
http://purl.bioontology.org/ontology/OMIM/181500 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036341 MedlinePlus Health Topics LOOM
http://purl.bmicc.cn/ontology/ICD11CN/6A20 International Classification of Diseases, 11th Edition, China LOOM
http://purl.bioontology.org/ontology/LNC/MTHU020814 Logical Observation Identifier Names and Codes LOOM
http://purl.obolibrary.org/obo/DOID_5419 International Classification of Diseases Ontology LOOM
http://purl.obolibrary.org/obo/DOID_5419 Human Disease Ontology 123 LOOM
http://purl.bioontology.org/ontology/ICD10CM/F20 International Classification of Diseases, Version 10 - Clinical Modification LOOM