Medical Subject Headings

Last uploaded: November 5, 2019

Preferred Name	telithromycin
Synonyms	HMR-3647
ID	http://purl.bioontology.org/ontology/MESH/C106791
altLabel	HMR-3647 HMR3647 Ketek HMR 3647 RU-66647 RU 66647
cui	C0907410 C0663674 C0540639 C1452484
HM	D048628
II	D011500 D012338
Inverse of RB	KI8H7H19WL 0
isa	http://purl.bioontology.org/ontology/MESH/D000900
LT	TRD
Mapped to	http://purl.bioontology.org/ontology/MESH/D048628
MDA	19970722
MeSH Frequency	595
MMR	20160818
notation	C106791
PA	D000900
PI	*MACROLIDES (1997-2004)
prefLabel	telithromycin
SC	1
Scope Statement	a ketolide; semisynthetic derivative of erythromycin with cycling of the C11-12 positions to form a carbamate ring to avoid acquired resistance to macrolides; binds 70S bacterial rRNA, specifically to the 23S part (23S RIBOSOMAL RNA), preventing protein synthesis;
SRC	Diagn Microbiol Infect Dis 1997 Jan-Feb;27(1-2):7-12 The Annals of Pharmacotherapy 2002 36:452-64
TERMUI	T308123 T364814 T308121 T308124 T591267 T591568 T308122
TH	NLM (2004) FDA SRS (2017) DE FR NLM (1997) INN (19XX) ES
tui	T109 T195

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_29688	Chemical Entities of Biological Interest Ontology	LOOM
http://purl.obolibrary.org/obo/CHEBI_29688	GenEpiO	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU016681	Logical Observation Identifier Names and Codes	CUI
http://purl.bioontology.org/ontology/LNC/MTHU016681	Logical Observation Identifier Names and Codes	LOOM
http://purl.bioontology.org/ontology/LNC/LP33364-8	Logical Observation Identifier Names and Codes	CUI
http://purl.bioontology.org/ontology/LNC/LP33364-8	Logical Observation Identifier Names and Codes	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61963	National Cancer Institute Thesaurus	LOOM