Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
ID
http://purl.bioontology.org/ontology/MESH/D009693
altLabel
Nucleic Acid Hybridizations
Genomic Hybridizations
Hybridizations, Nucleic Acid
Hybridization, Nucleic Acid
Genomic Hybridization
Hybridizations, Genomic
Acid Hybridization, Nucleic
Acid Hybridizations, Nucleic
Hybridization, Genomic
AN
IM general only; coord NIM with DNA or RNA or specific (IM); IN SITU HYBRIDIZATION & IN SITU HYBRIDIZATION, FLUORESCENCE are available
AQL
DE ES GE IM MT PH RE
cui
C0376343
C1300517
DC
1
definition
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
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