National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118965

code

C118965

DEFINITION

Leucine-rich repeat-containing G-protein coupled receptor 6 (967 aa, ~104 kDa) is encoded by the human LGR6 gene. This protein is involved in both binding to R-spondin proteins and potentiating ligand-dependent signaling pathways.

DesignNote

In contrast to classical G-protein coupled receptors, leucine-rich repeat-containing G-protein coupled receptor 6 does not appear to activate heterotrimeric G-proteins to transduce the signal. (UniProt)

FULL_SYN

Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6

label

Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6

NCI_META_CUI

CL480725

OMIM_Number

606653

Preferred_Name

Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6

prefixIRI

C118965

prefLabel

Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

Swiss_Prot

Q9HBX8

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18239

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/OMIM/606653 Online Mendelian Inheritance in Man LOOM
http://purl.obolibrary.org/obo/PR_000001593 Protein Ontology LOOM