National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Aryl Hydrocarbon Receptor Nuclear Translocator-Like Protein 1

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C119694

code

C119694

DEFINITION

Aryl hydrocarbon receptor nuclear translocator-like protein 1 (626 aa, ~69 kDa) is encoded by the human ARNTL gene. This protein is involved in transcriptional activation.

DesignNote

Aryl hydrocarbon receptor nuclear translocator-like protein 1 forms a heterodimer with circadian locomoter output cycles protein; the heterodimer can bind to E-box enhancer elements (5'-CACGTG-3'). The interaction of the heterodimeric complex with cryptochrome or period family transcriptional repressors inhibits the ability of the heterodimer to activate gene transcription. (UniProt)

FULL_SYN

Class E Basic Helix-Loop-Helix Protein 5

PAS Domain-Containing Protein 3

Brain and Muscle ARNT-Like Protein 1

Basic-Helix-Loop-Helix-PAS Protein MOP3

Brain and Muscle ARNT-Like 1

Member of PAS Protein 3

BHLH-PAS Protein JAP3

Member of PAS Superfamily 3

bHLHe5

label

Aryl Hydrocarbon Receptor Nuclear Translocator-Like Protein 1

NCI_META_CUI

CL480629

OMIM_Number

602550

Preferred_Name

Aryl Hydrocarbon Receptor Nuclear Translocator-Like Protein 1

prefixIRI

C119694

prefLabel

Aryl Hydrocarbon Receptor Nuclear Translocator-Like Protein 1

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

O00327

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17207

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http://purl.obolibrary.org/obo/PR_000004305 Protein Ontology LOOM