loading...| Preferred Name |
Aflatoxin B1 |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1315 |
| ALT_DEFINITION |
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1. |
| CAS_Registry |
1162-65-8 |
| CHEBI_ID |
CHEBI:2504 |
| Chemical_Formula |
C17H12O6 |
| code |
C1315 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A member of a group of mycotoxins produced by Aspergillus flavus and A. parasiticus. Alflatoxin B1 is the most hepatotoxic and hepatocarcinogenic of the aflatoxins and occurs as a contaminant in a variety of foods. |
| FDA_UNII_Code |
9N2N2Y55MH |
| FULL_SYN |
(6AR-cis)-2,3,6a,9a-tetrahydro-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione AFB1 |
| label |
Aflatoxin B1 |
| Legacy_Concept_Name |
Aflatoxin_B1 |
| NSC_Code |
529592 |
| Preferred_Name |
Aflatoxin B1 |
| prefixIRI |
C1315 |
| prefLabel |
Aflatoxin B1 |
| Semantic_Type |
Organic Chemical Hazardous or Poisonous Substance |
| UMLS_CUI |
C0085180 |
| subClassOf |