National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Telomere

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13295

ALT_DEFINITION

The ends of a chromosome. Each time a cell divides, the telomeres lose a small amount of DNA and become shorter. Over time, the chromosomes become damaged and the cells die. In cancer cells the telomeres do not get shorter, and may become longer, as the cells divide.

code

C13295

DEFINITION

A stretch of repetitive nucleotide sequences (TTAGGG repeats in humans) found at both ends of each chromatid arm that plays a role in chromosome stability during replication.

FULL_SYN

Telomeres

label

Telomere

Legacy_Concept_Name

Telomere

Preferred_Name

Telomere

prefixIRI

C13295

prefLabel

Telomere

Semantic_Type

Cell Component

UMLS_CUI

C0085187

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13377

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http://purl.bioontology.org/ontology/MESH/D016615 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/SO_0000624 Sequence Types and Features Ontology LOOM
http://purl.bioontology.org/ontology/LNC/LP36159-9 Logical Observation Identifier Names and Codes LOOM