National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Internal Ribosome Entry Site

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13716

code

C13716

DEFINITION

Internal ribosome entry site (IRES) is a translational cis-acting element that directs ribosomes to the start codon by a cap-independent mechanism. IRESs are usually about 450 nucleotides in length and were first identified in picornavirus RNAs. IRESs can fold into a stable secondary hairpin structure to be incompatible with efficient translation by ribosomal scanning. (NCI)

FULL_SYN

Ribosome Entry Site

IRES

label

Internal Ribosome Entry Site

Legacy_Concept_Name

Internal_Ribosome_Entry_Site

Preferred_Name

Internal Ribosome Entry Site

prefixIRI

C13716

prefLabel

Internal Ribosome Entry Site

Semantic_Type

Gene or Genome

UMLS_CUI

C1512886

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13734

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/SO_0000243 MicroRNA Ontology LOOM
http://purl.obolibrary.org/obo/SO_0000243 Sequence Types and Features Ontology LOOM