National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Signaling Pathway

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17132

ALT_DEFINITION

Describes a group of molecules in a cell that work together to control one or more cell functions, such as cell division or cell death. After the first molecule in a pathway receives a signal, it activates another molecule. This process is repeated until the last molecule is activated and the cell function involved is carried out. Abnormal activation of signaling pathways can lead to cancer, and drugs are being developed to block these pathways. This may help block cancer cell growth and kill cancer cells.

code

C17132

DEFINITION

An elaboration of the known or inferred interactions involved in a signal transduction pathway.

FULL_SYN

Signal Transduction Pathway

label

Signaling Pathway

Legacy_Concept_Name

Signaling_Pathways

Preferred_Name

Signaling Pathway

prefixIRI

C17132

prefLabel

Signaling Pathway

Semantic_Type

Cell Function

UMLS_CUI

C0037080

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20633

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/PW_0000003 Pathway Ontology LOOM