National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Rhombotin-2

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17974

code

C17974

DEFINITION

Rhombotin-2 (158 aa, ~18 kDa) is encoded by the human LMO2 gene. This protein is involved in erythrocyte development.

DesignNote

With two LIM domains and a cysteine-rich motif, rhombotin 2 is part of a multi-protein transcription regulatory complex that includes GATA-1. LMO2 protein binds to the bHLH TAL1 protein and interacts with retinoblastoma binding protein-2, enhancing transcription.

FULL_SYN

TTG-2 Protein

Cysteine-Rich Protein TTG-2

Rhombotin 2

Rhombotin-Like 1

T-Cell Translocation Gene 2 Protein

LIM Domain Only Protein 2

T-Cell Translocation Protein

T-Cell Translocation Protein 2

LMO2

LMO2 Protein

LIM Domain Only 2

Rhombotin 2 Protein

Lim Domain Only 2 Protein

LIM-Only Protein 2

Rhombotin-Like 1 Protein

LMO-2

label

Rhombotin-2

Legacy_Concept_Name

Rhombotin-2

OMIM_Number

180385

Preferred_Name

Rhombotin-2

prefixIRI

C17974

prefLabel

Rhombotin-2

Semantic_Type

Biologically Active Substance

Amino Acid, Peptide, or Protein

Swiss_Prot

P25791

UMLS_CUI

C0250437

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26199

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http://purl.obolibrary.org/obo/PR_000009863 Protein Ontology LOOM