National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Pharmacologic Substance

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

ALT_DEFINITION

An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)).

An article other than food intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease; or intended to affect the structure or any function of the body. EXAMPLE(S): aspirin

Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.

CHEBI_ID

CHEBI:52217

code

C1909

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96388

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99078

Contributing_Source

CDISC

NICHD

BRIDG

DEFINITION

Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances.

DesignNote

This category represents ingredients, not drug products.

FULL_SYN

Agent

Pharmacologic Agent

DRUG

Pharmacological Substance

Drug Substance

Pharmaceutical Agent

Pharmaceuticals

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45306

label

Pharmacologic Substance

Legacy_Concept_Name

Pharmacologic_Substance

NICHD_Hierarchy_Term

Pharmacologic Substance

Preferred_Name

Pharmacologic Substance

prefixIRI

C1909

prefLabel

Pharmacologic Substance

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C1254351

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1908

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http://purl.bioontology.org/ontology/STY/T121 MedlinePlus Health Topics LOOM
http://purl.bioontology.org/ontology/STY/T121 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/STY/T121 International Classification of Diseases, Version 10 - Clinical Modification LOOM
http://purl.bioontology.org/ontology/STY/T121 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/STY/T121 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/STY/T121 Semantic Types Ontology LOOM