National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

PRC1

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19866

code

C19866

DEFINITION

PRC1 (Polycomb repressive complex 1) contains the products of the PcG genes Polycomb, Posterior sex combs, polyhomeotic, Sex combs on midleg, and several other proteins. Preincubation of PRC1 with nucleosomal arrays blocks the ability of these arrays to be remodeled by SWI/SNF. PRC1 and SWI/SNF are likely compete with each other for the nucleosomal template.

FULL_SYN

PRC1 Protein

Polycomb Repressive Complex 1

label

PRC1

Legacy_Concept_Name

PRC1

Preferred_Name

PRC1

prefixIRI

C19866

prefLabel

PRC1

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C1335252

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19814

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http://purl.obolibrary.org/obo/OGG_3000009055 Ontology of Genes and Genomes LOOM