National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Three Prime Repair Exonuclease 2

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21552

code

C21552

DEFINITION

Three prime repair exonuclease 2 (279 aa, ~31 kDa) is encoded by the human TREX2 gene. This protein is involved in the excision of 3' mismatched 3' termini from double-stranded DNA.

DesignNote

The gene encoding three prime repair exonuclease 2 is either overlapping or adjacent to the HAUS7 gene. Most mRNAs that encode HAUS augmin-like complex subunit 7 also include the N-terminal part of TREX2. (UniProt)

FULL_SYN

EC 3.1.11.2

TREX2

3'-5' Exonuclease TREX2 Long Form

3'-5' Exonuclease TREX2

label

Three Prime Repair Exonuclease 2

Legacy_Concept_Name

Three_Prime_Repair_Exonuclease_2

OMIM_Number

300370

Preferred_Name

Three Prime Repair Exonuclease 2

prefixIRI

C21552

prefLabel

Three Prime Repair Exonuclease 2

Semantic_Type

Enzyme

Amino Acid, Peptide, or Protein

Swiss_Prot

Q9BQ50

UMLS_CUI

C1432810

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21170

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http://purl.obolibrary.org/obo/PR_000016633 Protein Ontology LOOM