Preferred Name |
Vasopressin V1B Receptor |
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26097 |
code |
C26097 |
DEFINITION |
Vasopressin V1b receptor (424 aa, ~47 kDa) is encoded by the human AVPR1B gene. This protein plays a role in G protein-coupled receptor signaling mediated by vasopressin. |
DesignNote |
This protein acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. |
FULL_SYN |
V1bR AVPR V3 AVPR1B AVPR V1b Arginine Vasopressin Receptor 3 Arginine Vasopressin Receptor 1B Antidiuretic Hormone Receptor 1B Pituitary Vasopressin Receptor 3 |
label |
Vasopressin V1B Receptor |
Legacy_Concept_Name |
Arginine_Vasopressin_Receptor-1B |
OMIM_Number |
600264 |
Preferred_Name |
Vasopressin V1B Receptor |
prefixIRI |
C26097 |
prefLabel |
Vasopressin V1B Receptor |
Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
Swiss_Prot |
P47901 |
UMLS_CUI |
C0284726 |
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/PR_000001682 | Protein Ontology | LOOM |