National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Famciclovir

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29044

CAS_Registry

104227-87-4

CHEBI_ID

CHEBI:4974

Chemical_Formula

C14H19N5O4

code

C29044

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04)

FDA_UNII_Code

QIC03ANI02

FULL_SYN

2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol Diacetate (ester)

BRL-42810

Famvir

BRL 42810

label

Famciclovir

Legacy_Concept_Name

Famciclovir

Preferred_Name

Famciclovir

prefixIRI

C29044

prefLabel

Famciclovir

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0209227

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29575

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C281

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/MESH/D000077595 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/CHEBI_4974 Chemical Entities of Biological Interest Ontology LOOM
http://purl.bioontology.org/ontology/LNC/LP157326-2 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/LNC/MTHU045606 Logical Observation Identifier Names and Codes LOOM