National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Choriocarcinoma

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2948

ALT_DEFINITION

A malignant neoplasm arising from placental trophoblast cells. They generally arise in the uterus.

A malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all choriocarcinomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary. Choriocarcinomas spread through the blood to other organs, especially the lungs. They are a type of gestational trophoblastic disease.

code

C2948

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88025

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526

Contributing_Source

CDISC

DEFINITION

An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.

FULL_SYN

CHORIOCARCINOMA, MALIGNANT

chorioblastoma

Chorioepithelioma

chorionic carcinoma

ICD-O-3_Code

9100/3

label

Choriocarcinoma

Legacy_Concept_Name

Choriocarcinoma

Neoplastic_Status

Malignant

Preferred_Name

Choriocarcinoma

prefixIRI

C2948

prefLabel

Choriocarcinoma

Semantic_Type

Neoplastic Process

UMLS_CUI

C0008497

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3422

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http://purl.obolibrary.org/obo/HP_0100768 Human Phenotype Ontology LOOM
http://purl.bioontology.org/ontology/MESH/D002822 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/DOID_3594 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) LOOM
http://purl.obolibrary.org/obo/DOID_3594 Human Disease Ontology 123 LOOM