National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Biotin

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C309

ALT_DEFINITION

Water-soluble vitamin that is a coenzyme in bicarbonate-dependent carboxylation.

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Biotin helps some enzymes break down substances in the body for energy and helps tissues develop. It is found in yeast, whole milk, egg yolks, and organ meats. Biotin is water-soluble (can dissolve in water) and must be taken in every day. Not enough biotin can cause skin, nerve, and eye disorders. Biotin is present in larger amounts in some cancer tissue than in normal tissue. Attaching biotin to substances used to treat some types of cancer helps them find cancer cells.

CAS_Registry

58-85-5

CHEBI_ID

CHEBI:15956

Chemical_Formula

C10H16N2O3S

code

C309

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid. Growth factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tissue is higher than that of normal tissue.

FDA_UNII_Code

6SO6U10H04

FULL_SYN

5-(3-oxo-7-thia-2,4-diazabicyclo[3.3.0]oct-8-yl)pentanoic acid

Vitamin B-7

-(+)-Biotin

Vitamin H

(+)-Biotin

INFOODS

BIOT

label

Biotin

Legacy_Concept_Name

Biotin

Micronutrient

Y

NSC_Code

63865

Nutrient

Y

Preferred_Name

Biotin

prefixIRI

C309

prefLabel

Biotin

Semantic_Type

Organic Chemical

Vitamin

UMLS_CUI

C0005575

Unit

mcg

US_Recommended_Intake

Y

USDA_ID

416

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45812

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