loading...| Preferred Name |
Toxic Shock Syndrome |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35498 |
| ALT_DEFINITION |
A severe illness caused by infection with staphylococcus aureus and characterized by high fever of sudden onset, vomiting, diarrhea, and myalgia, followed by hypotension and in severe cases, shock; a sunburn-like rash with peeling of the skin, especially of the palms and soles, occurs during the acute phase. syndrome characterized by high fever, vomiting, diarrhea, confusion, and skin rash; almost all cases have been related to an infection with toxin-producing Staphylococcus aureus. Profoundly reduced blood flow that results in impaired tissue perfusion and possible end organ damage resulting from an enterotoxin released from certain bacteria, most often Staphylococcus aureus, or Streptococcus pyogenes. |
| code |
C35498 |
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464 |
| Contributing_Source |
NICHD MedDRA FDA |
| DEFINITION |
A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria. |
| FDA_Table |
Patient Code (Appendix B) |
| FULL_SYN |
Toxic Shock Syndrome, (TSS) Syndrome (TSS), Toxic Shock Shock Syndrome (TSS), Toxic TSS, Toxic Shock Syndrome |
| Has_CDRH_Parent | |
| Has_NICHD_Parent | |
| label |
Toxic Shock Syndrome |
| Legacy_Concept_Name |
Toxic_Shock_Syndrome |
| NICHD_Hierarchy_Term |
Toxic Shock Syndrome |
| Preferred_Name |
Toxic Shock Syndrome |
| prefixIRI |
C35498 |
| prefLabel |
Toxic Shock Syndrome |
| Semantic_Type |
Disease or Syndrome |
| UMLS_CUI |
C0600327 |
| subClassOf |