National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Insulin Signaling Pathway
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39130
ALT_DEFINITION	The appropriate signaling through the insulin pathway is critical for the regulation of glucose levels and the avoidance of diabetes. Insulin forms a complex with the insulin receptor (IR) and b chains to form the active signaling complex. Through recruitment of adaptor molecules and the activation of RAS, the activated IR can cause transcriptional activation.
BioCarta_ID	h_insulinPathway
code	C39130
label	Insulin Signaling Pathway
Legacy_Concept_Name	Insulin_Signaling_Pathway
Preferred_Name	Insulin Signaling Pathway
prefixIRI	C39130
prefLabel	Insulin Signaling Pathway
Semantic_Type	Functional Concept
UMLS_CUI	C1512804
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17132

Delete	Subject	Author	Type	Created
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Delete	Mapping To	Ontology	Source
	http://purl.obolibrary.org/obo/PW_0000143	Pathway Ontology	LOOM