National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Hematopoiesis Pathway

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39240

ALT_DEFINITION

The process of hematopoiesis is regulated by various cytokines. The combination of cytokines stimulates the proliferation and/or differentiation of the various hematopoietic cell types. Bone marrow stromal cells are the major source of hematopoietic cytokines in the non-infectious state. In the presence of infection, cytokines produced by activated macrophages and TH cells induce hematopoietic activity. The induction by cytokines results in rapid expansion of the population of white blood cells to fight infection.

BioCarta_ID

h_stemPathway

code

C39240

FULL_SYN

Regulation of hematopoiesis by cytokines

label

Hematopoiesis Pathway

Legacy_Concept_Name

Hematopoiesis_Pathway

Preferred_Name

Hematopoiesis Pathway

prefixIRI

C39240

prefLabel

Hematopoiesis Pathway

Semantic_Type

Functional Concept

UMLS_CUI

C1512384

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C39704

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http://purl.obolibrary.org/obo/PW_0000660 Pathway Ontology LOOM