National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Heart Failure

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50577

ALT_DEFINITION

A disorder characterized by the inability of the heart to pump blood at an adequate volume to meet tissue metabolic requirements, or, the ability to do so only at an elevation in the filling pressure.

Inability of the heart to pump blood at an adequate rate to fill tissue metabolic requirements or the ability to do so only at an elevated filling pressure.

Inability of the heart to meet tissue metabolic requirements.

code

C50577

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450

Contributing_Source

NICHD

MedDRA

CTCAE

FDA

DEFINITION

Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction.

FDA_Table

Patient Code (Appendix B)

FULL_SYN

Failure, Heart

Insufficiency, Cardiac

Cardiac Failure

Cardiac Insufficiency

Has_CDRH_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54027

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3079

label

Heart Failure

Legacy_Concept_Name

Heart_Failure

NICHD_Hierarchy_Term

Heart Failure

Preferred_Name

Heart Failure

prefixIRI

C50577

prefLabel

Heart Failure

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0018801

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35741

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http://purl.bioontology.org/ontology/ICD10CM/I50 International Classification of Diseases, Version 10 - Clinical Modification LOOM
http://purl.obolibrary.org/obo/SYMP_0000292 Human Disease Ontology 123 LOOM
http://purl.bmicc.cn/ontology/ICD11CN/L1-BD1 International Classification of Diseases, 11th Edition, China LOOM
http://purl.bioontology.org/ontology/MESH/D006333 Medical Subject Headings LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU009472 Online Mendelian Inheritance in Man LOOM
http://purl.bioontology.org/ontology/ICD10/I50 International Classification of Diseases, Version 10 LOOM