National Cancer Institute Thesaurus

Last uploaded: February 21, 2019

Preferred Name	Azlocillin Sodium
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65243
CAS_Registry	37091-65-9
CHEBI_ID	CHEBI:51864
Chemical_Formula	C20H22N5O6S.Na
code	C65243
Concept_In_Subset	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923
Contributing_Source	FDA
DEFINITION	The sodium salt form of azlocillin, a semisynthetic, extended spectrum acylampicillin with antibacterial activity. Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis.
FDA_UNII_Code	DWV1EFW947
Has_Free_Acid_Or_Base_Form	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C293
label	Azlocillin Sodium
Legacy_Concept_Name	Azlocillin_Sodium
Preferred_Name	Azlocillin Sodium
prefixIRI	C65243
prefLabel	Azlocillin Sodium
Semantic_Type	Pharmacologic Substance
UMLS_CUI	C0701436
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500

Delete	Subject	Author	Type	Created
No notes to display

Delete	Mapping To	Ontology	Source
	http://purl.obolibrary.org/obo/CHEBI_51864	Chemical Entities of Biological Interest Ontology	LOOM