National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

T-Cell Surface Glycoprotein CD5

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73124

code

C73124

DEFINITION

T-cell surface glycoprotein CD5 (495 aa, ~54 kDa) is encoded by the human CD5 gene. This protein may be involved in regulating the proliferation of T-cells.

DesignNote

T-cell surface glycoprotein CD5 is a membrane bound glycoprotein expressed on all mature T-cells, thymocytes, and a subset of mature B-cells. Antibodies that specifically bind to CD5 can enhance T-cell receptor-mediated T-cell activation. This protein can bind to CD72 antigen. (Abbas et al., Cellular and Molecular Immunology, 2d ed, p156)

FULL_SYN

CD5

CD5 Antigen

Lymphocyte Antigen CD5

Lymphocyte Antigen T1/Leu-1

label

T-Cell Surface Glycoprotein CD5

Legacy_Concept_Name

T-Cell_Surface_Glycoprotein_CD5

OMIM_Number

153340

Preferred_Name

T-Cell Surface Glycoprotein CD5

prefixIRI

C73124

prefLabel

T-Cell Surface Glycoprotein CD5

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P06127

UMLS_CUI

C0054964

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17728

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http://purl.obolibrary.org/obo/PR_000001839 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001839 Cell Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001839 Protein Ontology LOOM
http://purl.obolibrary.org/obo/PR_000001839 Cell Line Ontology Subset for Chinese National Infrastructure of Cell Line Resource (NICR) LOOM