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loading...| Preferred Name |
Emivirine |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73147 |
| CAS_Registry |
149950-60-7 |
| CHEBI_ID |
CHEBI:44143 |
| Chemical_Formula |
C17H22N2O3 |
| code |
C73147 |
| Concept_In_Subset | |
| Contributing_Source |
FDA |
| DEFINITION |
A non-nucleoside reverse transcriptase inhibitor. Emivirine has a structure typical of a nucleoside analog but has been shown to bind directly to the reverse transcriptase and act as an NNRTI. However, it is no longer in development due to the fact that it causes an increasingly rapid breakdown of other drugs metabolized by the cytochrome P450 enzyme. |
| FDA_UNII_Code |
X87G8IX72O |
| FULL_SYN |
Coactinon 6-benzyl-1-(ethoxymethyl)-5-isopropyl-uracil MKC-442 EMV |
| label |
Emivirine |
| Legacy_Concept_Name |
Emivirine |
| Preferred_Name |
Emivirine |
| prefixIRI |
C73147 |
| prefLabel |
Emivirine |
| Semantic_Type |
Pharmacologic Substance |
| UMLS_CUI |
C0248121 |
| subClassOf |
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| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/CHEBI_44143 | Chemical Entities of Biological Interest Ontology | LOOM | |
| http://purl.bioontology.org/ontology/MESH/C083858 | Medical Subject Headings | LOOM |