National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
Preferred Name

Pumitepa

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73239

CAS_Registry

42061-52-9

Chemical_Formula

C12H19N8OP

code

C73239

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A thiotepa derivative with potential antineoplastic alkylating activity. Although the exact mechanism of action of pumitepa has yet to be fully elucidated, this agent appears to work through alkylation, thereby causing DNA damage and cell cycle arrest.

FDA_UNII_Code

7AYY495RE0

FULL_SYN

Fopurin

label

Pumitepa

Legacy_Concept_Name

Pumitepa

Preferred_Name

Pumitepa

prefixIRI

C73239

prefLabel

Pumitepa

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0060632

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1590

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