loading...| Preferred Name |
Spliceosome Pathway |
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91451 |
| ALT_DEFINITION |
After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified. |
| code |
C91451 |
| FULL_SYN |
Spliceosome |
| KEGG_ID |
hsa03040 |
| label |
Spliceosome Pathway |
| Preferred_Name |
Spliceosome Pathway |
| prefixIRI |
C91451 |
| prefLabel |
Spliceosome Pathway |
| Semantic_Type |
Functional Concept |
| UMLS_CUI |
C2984264 |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/PW_0001073 | Pathway Ontology | LOOM |