National Cancer Institute Thesaurus

Last uploaded: February 21, 2019
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Preferred Name

Activation of Membrane Attack Complex
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92160
code

C92160
DEFINITION

A series of reactions that result in formation of a pore, composed of complement proteins C5b, C6, C7, C8, and C9, in the membrane of a pathogenic cell. The pore allows free diffusion of molecules into and out of the cell and reduces cell viability.
label

Activation of Membrane Attack Complex
NCI_META_CUI

CL449111
Preferred_Name

Activation of Membrane Attack Complex
prefixIRI

C92160
prefLabel

Activation of Membrane Attack Complex
Semantic_Type

Phenomenon or Process
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21519
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http://purl.obolibrary.org/obo/GO_0001905 Gene Ontology LOOM