Ontology for Biomedical Investigations

Last uploaded: January 23, 2019
Preferred Name

methylation-specific polymerase chain reaction assay

Definitions

An assay that uses initial modification of DNA by sodium bisulfite, converting all unmethylated, but not methylated, cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA.

ID

http://purl.obolibrary.org/obo/OBI_0001684

alternative term

MSP

definition source

PMID:8790415

editor preferred label

methylation-specific polymerase chain reaction assay

example of usage

Methylation status of breast cancer resistance protein detected by methylation-specific polymerase chain reaction analysis is correlated inversely with its expression in drug-resistant lung cancer cells. PMID:18219662

has curation status

http://purl.obolibrary.org/obo/IAO_0000122

has_specified_output

http://purl.obolibrary.org/obo/IAO_0000027

label

methylation-specific polymerase chain reaction assay

prefixIRI

OBI:0001684

prefLabel

methylation-specific polymerase chain reaction assay

term editor

Philippe Rocca-Serra

Marcus Chibucos

textual definition

An assay that uses initial modification of DNA by sodium bisulfite, converting all unmethylated, but not methylated, cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA.

subClassOf

http://purl.obolibrary.org/obo/OBI_0000070

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http://purl.obolibrary.org/obo/OBI_0001684 Evidence and Conclusion Ontology LOOM
http://purl.obolibrary.org/obo/OBI_0001684 Evidence and Conclusion Ontology SAME_URI