Ontology for Biomedical Investigations

Last uploaded: January 23, 2019
Preferred Name

chromatin immunoprecipitation with exonuclease sequencing assay

Definitions

A ChIP-seq assay which uses immunoprecipitation to isolate protein bound DNA followed by an exonuclease step to degrade DNA that is not protein bound to provide greater resolution of the DNA binding site

ID

http://purl.obolibrary.org/obo/OBI_0001925

alternative term

ChIP-exo assay

definition source

PMID:22153082

editor preferred label

chromatin immunoprecipitation with exonuclease sequencing assay

example of usage

Rhee et al. Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution. Cell. 2011 Dec;147(6):1408-19. [PMID:22153082]

has curation status

http://purl.obolibrary.org/obo/IAO_0000120

has part

http://purl.obolibrary.org/obo/OBI_0600050

http://purl.obolibrary.org/obo/OBI_0000800

has_specified_output

http://purl.obolibrary.org/obo/OBI_0001573

label

chromatin immunoprecipitation with exonuclease sequencing assay

prefixIRI

OBI:0001925

prefLabel

chromatin immunoprecipitation with exonuclease sequencing assay

term editor

Bjoern Peters

Chris Stoeckert

Venkat Malladi

Jie Zheng

textual definition

A ChIP-seq assay which uses immunoprecipitation to isolate protein bound DNA followed by an exonuclease step to degrade DNA that is not protein bound to provide greater resolution of the DNA binding site

subClassOf

http://purl.obolibrary.org/obo/OBI_0000716

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http://purl.obolibrary.org/obo/OBI_0001925 Evidence and Conclusion Ontology LOOM
http://purl.obolibrary.org/obo/OBI_0001925 Evidence and Conclusion Ontology SAME_URI