loading...| Preferred Name |
CD3 subunit with immunoglobulin domain |
| Definitions |
A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. |
| ID |
http://purl.obolibrary.org/obo/PR_000001018 |
| editor preferred label |
CD3 subunit with immunoglobulin domain |
| imported from | |
| label |
CD3 subunit with immunoglobulin domain |
| prefixIRI |
PR:000001018 |
| prefLabel |
CD3 subunit with immunoglobulin domain |
| textual definition |
A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. |
| subClassOf |