loading...| Preferred Name |
prefoldin complex |
| Synonyms |
GIM complex |
| Definitions |
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. |
| ID |
http://purl.obolibrary.org/obo/GO_0016272 |
| definition |
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. |
| has_narrow_synonym |
GIM complex |
| has_obo_namespace |
cellular_component |
| id |
GO:0016272 |
| label |
prefoldin complex |
| notation |
GO:0016272 |
| prefLabel |
prefoldin complex |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0016272 | Gene Ontology | LOOM | |
| http://purl.obolibrary.org/obo/GO_0016272 | Gene Ontology | SAME_URI |