loading...| Preferred Name |
interferon regulatory factor complex |
| Synonyms |
IRF complex |
| Definitions |
A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. |
| ID |
http://purl.obolibrary.org/obo/GO_0097071 |
| definition |
A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. |
| has_exact_synonym |
IRF complex |
| has_obo_namespace |
cellular_component |
| id |
GO:0097071 |
| label |
interferon regulatory factor complex |
| notation |
GO:0097071 |
| prefLabel |
interferon regulatory factor complex |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0097071 | Gene Ontology | LOOM | |
| http://purl.obolibrary.org/obo/GO_0097071 | Gene Ontology | SAME_URI |