Pathway Ontology

Last uploaded: January 13, 2022

Preferred Name	Toll-like receptor signaling pathway
Synonyms	Toll-Like Receptors Cascades TLR signaling pathway
Definitions	Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators.
ID	http://purl.obolibrary.org/obo/PW_0000814
created_by	VPetri
creation_date	2010-10-27T11:29:27Z
definition	Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators.
has_alternative_id	Reactome:R-HSA-168898 KEGG:04620
has_obo_namespace	pathway
has_related_synonym	Toll-Like Receptors Cascades TLR signaling pathway
id	PW:0000814
label	Toll-like receptor signaling pathway
notation	PW:0000814
prefLabel	Toll-like receptor signaling pathway
treeView	http://purl.obolibrary.org/obo/PW_0000925
subClassOf	http://purl.obolibrary.org/obo/PW_0000925

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Delete	Mapping To	Ontology	Source
	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C91505	National Cancer Institute Thesaurus	LOOM
	http://purl.obolibrary.org/obo/GO_0002224	Gene Ontology	LOOM