loading...| Preferred Name |
peroxisome proliferator-activated receptor signaling pathway |
| Synonyms |
PPAR signaling pathway |
| Definitions |
Peroxisome proliferator-activated receptor signaling is initiated in response to binding several compounds within classes of lipids such as the eicosanoid, leukotriene, prostagladin, among others. The receptors form heterodimers with the retinoid X receptor, bind to specific DNA elements and regulate the expression of target genes. Deregulation of the pathway has been implicated in several conditions. |
| ID |
http://purl.obolibrary.org/obo/PW_0001355 |
| created_by |
VPetri |
| creation_date |
2013-06-05T08:45:28Z |
| definition |
Peroxisome proliferator-activated receptor signaling is initiated in response to binding several compounds within classes of lipids such as the eicosanoid, leukotriene, prostagladin, among others. The receptors form heterodimers with the retinoid X receptor, bind to specific DNA elements and regulate the expression of target genes. Deregulation of the pathway has been implicated in several conditions. |
| has_exact_synonym |
PPAR signaling pathway |
| has_obo_namespace |
pathway |
| id |
PW:0001355 |
| label |
peroxisome proliferator-activated receptor signaling pathway |
| notation |
PW:0001355 |
| prefLabel |
peroxisome proliferator-activated receptor signaling pathway |
| treeView | |
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/GO_0035357 | Gene Ontology | LOOM |