loading...| Preferred Name |
keratinocyte |
| Synonyms |
keratinized cell of epidermis malpighian cell |
| Definitions |
An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. |
| ID |
http://purl.obolibrary.org/obo/CL_0000312 |
| comment |
Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. |
| capable of |
http://purl.obolibrary.org/obo/GO_0090023 |
| database_cross_reference |
CALOHA:TS-0500 FMA:62879 BTO:0000667 |
| definition |
An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
| has_alternative_id |
CL:0002185 |
| has_exact_synonym |
keratinized cell of epidermis malpighian cell |
| has_obo_namespace |
cell |
| label |
keratinocyte |
| part_of | |
| prefixIRI |
CL:0000312 |
| prefLabel |
keratinocyte |
| treeView | |
| subClassOf |
http://purl.obolibrary.org/obo/BFO_0000040 |