Cell Ontology

Last uploaded: February 23, 2022
Preferred Name

monocyte

Definitions

Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.

ID

http://purl.obolibrary.org/obo/CL_0000576

comment

Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.

capable of

http://purl.obolibrary.org/obo/GO_0030316

http://purl.obolibrary.org/obo/GO_0030225

http://purl.obolibrary.org/obo/GO_0043011

database_cross_reference

CALOHA:TS-0638

BTO:0000876

FMA:62864

definition

Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.

develops_from

http://purl.obolibrary.org/obo/CL_0000559

has_obo_namespace

cell

label

monocyte

prefixIRI

CL:0000576

prefLabel

monocyte

treeView

http://purl.obolibrary.org/obo/CL_0000559

subClassOf

http://purl.obolibrary.org/obo/CL_0000842

http://purl.obolibrary.org/obo/CL_0011026

http://purl.obolibrary.org/obo/CL_0000766

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http://purl.obolibrary.org/obo/CL_0000576 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CL_0000576 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/CL_0000576 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/CL_0000576 Phenotypic Quality Ontology SAME_URI
http://www.semanticweb.org/ontologies/2009/3/ontoDPN.owl#Monocyte Early Pregnancy Ontology LOOM
http://purl.obolibrary.org/obo/BTO_0000876 BRENDA Tissue and Enzyme Source Ontology LOOM
http://purl.obolibrary.org/obo/FMA_62864 Foundational Model of Anatomy LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12547 National Cancer Institute Thesaurus LOOM