Preferred Name

macrophage

Synonyms

组织细胞

histiocyte

Definitions

形态:直径30µM-80µM,细胞质丰富,N/C比率低,偏心核。伪足形状不规则,高度粘结。含有空泡和吞噬体,可能含有嗜苯胺颗粒;标记:鼠标&人类:CD68,大多数情况下是CD11b。鼠标:大多数情况下是F4/80+;作用或过程:免疫,抗原呈递,&组织重塑;血统:造血,髓系。 A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.

ID

http://purl.obolibrary.org/obo/CL_0000235

comment

形态:直径30µM-80µM,细胞质丰富,N/C比率低,偏心核。伪足形状不规则,高度粘结。含有空泡和吞噬体,可能含有嗜苯胺颗粒;标记:鼠标&人类:CD68,大多数情况下是CD11b。鼠标:大多数情况下是F4/80+;作用或过程:免疫,抗原呈递,&组织重塑;血统:造血,髓系。

Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.

capable of

http://purl.obolibrary.org/obo/GO_0031268

http://purl.obolibrary.org/obo/GO_0006909

database_cross_reference

BTO:0000801

CALOHA:TS-0587

FMA:63261

FMA:83585

develops_from

http://purl.obolibrary.org/obo/CL_0000576

label

巨噬细胞

macrophage

prefixIRI

CL:0000235

prefLabel

macrophage

textual definition

A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.

存在于多种组织中的单核吞噬细胞,通常由单核细胞分化,能够吞噬各种细胞外颗粒物质,包括免疫复合物、微生物和死亡细胞。

treeView

http://purl.obolibrary.org/obo/CL_0000576

引自

http://purl.obolibrary.org/obo/clo.owl

http://purl.obolibrary.org/obo/cl.owl

有_obo_命名空间

细胞

cell

有_精确的_同义词

组织细胞

histiocyte

subClassOf

http://purl.obolibrary.org/obo/CL_0000234

http://purl.obolibrary.org/obo/CL_0000766

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12558 National Cancer Institute Thesaurus LOOM
http://purl.obolibrary.org/obo/BTO_0000801 BRENDA Tissue and Enzyme Source Ontology LOOM
http://purl.obolibrary.org/obo/CL_0000235 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/CL_0000235 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/CL_0000235 Phenotypic Quality Ontology LOOM
http://purl.obolibrary.org/obo/CL_0000235 Phenotypic Quality Ontology SAME_URI
http://purl.obolibrary.org/obo/CL_0000235 Cell Ontology LOOM
http://purl.obolibrary.org/obo/CL_0000235 Cell Ontology SAME_URI
http://purl.obolibrary.org/obo/CL_0000235 Cell Line Ontology (Chinese Translation) SAME_URI
http://purl.obolibrary.org/obo/CL_0000235 Ontology for Biomedical Investigations LOOM
http://purl.obolibrary.org/obo/CL_0000235 Ontology for Biomedical Investigations SAME_URI
http://purl.obolibrary.org/obo/CL_0000235 Human Disease Ontology 123 LOOM
http://purl.obolibrary.org/obo/CL_0000235 Human Disease Ontology 123 SAME_URI
http://www.semanticweb.org/ontologies/2009/3/ontoDPN.owl#Macrophage Early Pregnancy Ontology LOOM
http://purl.obolibrary.org/obo/FMA_63261 Foundational Model of Anatomy LOOM