Gene Ontology

Last uploaded: February 21, 2019
Preferred Name

gene silencing

Synonyms

long-term maintenance of gene inactivation

Definitions

This is a rather broad grouping term. While it was originally defined for long-term, heritable, epigenetic effects, short term effects on expression mediated by RNA are also frequently referred to as gene silencing, and are grouped under this class. Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.

ID

http://purl.obolibrary.org/obo/GO_0016458

comment

This is a rather broad grouping term. While it was originally defined for long-term, heritable, epigenetic effects, short term effects on expression mediated by RNA are also frequently referred to as gene silencing, and are grouped under this class.

database_cross_reference

Wikipedia:Gene_silencing

definition

Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.

has_narrow_synonym

long-term maintenance of gene inactivation

has_obo_namespace

biological_process

id

GO:0016458

in_subset

http://purl.obolibrary.org/obo/go#goslim_pir

label

gene silencing

notation

GO:0016458

prefLabel

gene silencing

treeView

http://purl.obolibrary.org/obo/GO_0010629

http://purl.obolibrary.org/obo/GO_0009987

subClassOf

http://purl.obolibrary.org/obo/GO_0010629

http://purl.obolibrary.org/obo/GO_0009987

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http://purl.bioontology.org/ontology/MESH/D020868 Medical Subject Headings LOOM
http://purl.obolibrary.org/obo/GO_0016458 Human Phenotype Ontology China LOOM
http://purl.obolibrary.org/obo/GO_0016458 Human Phenotype Ontology China SAME_URI
http://purl.obolibrary.org/obo/GO_0016458 Evidence and Conclusion Ontology LOOM
http://purl.obolibrary.org/obo/GO_0016458 Evidence and Conclusion Ontology SAME_URI